Ketomac Cream

Ketomac cream contains the broad-spectrum synthetic antifungal agent, Ketoconazole 2%. Ketoconazole is an imidazole antifungal agent.

Mechanism Of Action

Ketoconazole kills fungi and yeasts by interfering with their cell membranes. It works by impairing the synthesis of ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane. Cell membrane of fungi is vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As ketoconazole causes holes to appear in the cell membranes, essential constituents of the fungal cells leak out. This kills the fungi and clears up the infection.


Ketomac Cream is an antifungal medication that prevents fungus from growing on skin. It is used to treat fungal and yeast infections of the skin.It is indicated for the topical treatment of cutaneous candidiasis caused by candida spp. It is used to treat Ringworm (tinea corporis), jock itch (tinea cruris), athlete’s foot (tinea pedis) and dry, flaking skin, inflammatory skin condition with greasy, red and scaly areas (seborrheic dermatitis).

How To Use

Clean and thoroughly dry the area to be treated. Apply a thin layer of the cream to the affected skin. Apply enough medication to cover the affected skin and some of the surrounding skin. Do not wrap, cover or bandage over the treated skin unless directed to do so by your doctor. Wait at least 20 minutes after applying for this medicine before you use cosmetics or sunscreen on the treated skin area. Do not wash the treated skin for at least 3 hours after applying Ketomac cream. Use only once or twice a day or as directed by your doctor. This medicine is usually used for only 2 to 4 weeks.

Frequency Of Use

Usual Paediatric Dose For ringworm

Apply to the affected area once to twice a day.

Usual Adult Dose For Ringworm

Apply to the affected and surrounding area once to twice a day for 2 weeks.

Usual Adult Dose For Seborrheic Dermatitis

Apply to affected areas twice a day for 4 weeks or until clinical clearing.

Usual Adult Dose For Athlete’s foot

Apply to the affected and surrounded area once to twice a day for 6 weeks.


Ketomac cream is contraindicated in persons when hypersensitive to the active or excipient ingredients of this formulation.

Side Effects: Stinging, swelling, irritation, or redness of the treated skin may occur. If any of these effects persist or worsen, notify the physician promptly.

Precautions: Avoid covering treated skin areas with tight-fitting, synthetic clothing that doesn’t allow air to circulate to skin. If treating feet, wear clean cotton socks and sandals or shoes that allow for air circulation. Keep your feet dry. Do not use other medicated skin products unless prescribed by a physician.

Storage: Store in a cool & dry place. Protect from light. Do not freeze.

Presentation: Ketomac cream is supplied in a 15 gram tube.

For External Use Only