Local burning sensation, itching, or contact dermatitis (due to irritation or allergy) may occur in exposed areas. Oily and dry hair has rarely been reported with Ketoconazole shampoo. Hair discoloration has been observed in rare instances, mainly in patients with chemically damaged or grey hair.
Inform your doctor or pharmacist if you are allergic to Ketoconazole or other azole antifungal drugs (such as fluconazole and itraconazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. The product should be used with caution in people having liver problems, alcohol use, low testosterone levels, decreased adrenal gland function problems (such as low cortisol levels, Addison’s disease, adrenal insufficiency), and little or no stomach acid production (achlorhydria).
Ketoconazole is not absorbed into the bloodstream from the skin and is not harmful if used during pregnancy and breastfeeding. Ketoconazole is not detected in plasma after continuous shampooing for an extended period. Nevertheless, caution should be exercised when Ketomac shampoo 2% is administered to a nursing woman.